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Tbh - Tyramine beta hydroxylase

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen. Involved in several processes, including behavioral response to ethanol; inter-male aggressive behavior; and learning or memory. Predicted to be active in extracellular space and secretory granule membrane. Is expressed in several structures, including adult brain; adult central complex; octopaminergic neurons; synaptic neuropil domain; and ventral nerve cord. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; dopamine beta-hydroxylase deficiency; hypertension; and migraine with aura. Orthologous to human DBH (dopamine beta-hydroxylase). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Tbh

NCBI Orthologs

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Species Gene Architecture aa