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CG1409 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31689, updated on 9-Dec-2024

Summary

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Official Symbol
CG1409provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029964
Locus tag
Dmel_CG1409
See related
AllianceGenome:FB:FBgn0029964
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:AT29287; D.M.BLPp; Dmel\CG1409
Summary
Predicted to be involved in protein import into mitochondrial matrix. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in testis. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Megarbane-Dagher-Melike type. Orthologous to human PAM16 (presequence translocase associated motor 16). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG1409 in Genome Data Viewer
Location:
7C1-7C1; 1-21 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7858173..7858794)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7752206..7752827)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Carbonic anhydrase-related protein A Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 7b Neighboring gene antisense RNA:CR43615 Neighboring gene defective chorion

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The black-pearl gene of Drosophila defines a novel conserved protein family and is required for larval growth and survival. Becker S, et al. Gene, 2001 Jan 10. PMID 11179663
  2. Readapting to DCV Infection without Wolbachia: Frequency Changes of Drosophila Antiviral Alleles Can Replace Endosymbiont Protection. Faria VG, et al. Genome Biol Evol, 2018 Jul 1. PMID 29947761, Free PMC Article
  3. Analysis of Drosophila melanogaster testis transcriptome. Vedelek V, et al. BMC Genomics, 2018 Sep 24. PMID 30249207, Free PMC Article
  4. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article
  5. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in protein import into mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein import into mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of TIM23 mitochondrial import inner membrane translocase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1409-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    7858173..7858794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132181.2 → NP_572409.2  uncharacterized protein Dmel_CG1409 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572409.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DMN1, Q9W3P5
    Conserved Domains (1) summary
    cl02542
    Location:1 → 113
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MZ64 Q8MZ64
Q9W3P5 Q9W3P5

Gene LinkOut

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