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Atg5 - Autophagy-related 5

Predicted to contribute to Atg8-family ligase activity. Involved in cellular response to starvation; glycophagy; and larval midgut cell programmed cell death. Located in autophagosome. Is expressed in adult head; organism; and salivary gland. Used to study hereditary ataxia. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 25. Orthologous to human ATG5 (autophagy related 5). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa