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Cyp20a1 cytochrome P450, family 20, subfamily a, polypeptide 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 316435, updated on 27-Nov-2024

Summary

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Official Symbol
Cyp20a1provided by RGD
Official Full Name
cytochrome P450, family 20, subfamily a, polypeptide 1provided by RGD
Primary source
RGD:735221
See related
EnsemblRapid:ENSRNOG00000017631 AllianceGenome:RGD:735221
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be located in membrane. Orthologous to human CYP20A1 (cytochrome P450 family 20 subfamily A member 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 139.2), Heart (RPKM 127.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Cyp20a1 in Genome Data Viewer
Location:
9q32
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (69249841..69299146)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (61755804..61805123)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (67130222..67179693)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene neurobeachin-like 1 Neighboring gene peptidyl-prolyl cis-trans isomerase NIMA-interacting 4-like Neighboring gene ATP synthase membrane subunit c locus 2, pseudogene 1 Neighboring gene abl-interactor 2 Neighboring gene Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 Neighboring gene uncharacterized LOC102547711

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome P450 20A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199401.1 → NP_955433.1  cytochrome P450 20A1

    See identical proteins and their annotated locations for NP_955433.1

    Status: PROVISIONAL

    Source sequence(s)
    BC061716
    UniProtKB/Swiss-Prot
    Q6P7D4
    UniProtKB/TrEMBL
    F1LSK6
    Related
    ENSRNOP00000023796.4, ENSRNOT00000023796.6
    Conserved Domains (1) summary
    cl12078
    Location:43 → 415
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    69249841..69299146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017596467.3 → XP_017451956.1  cytochrome P450 20A1 isoform X1

    Conserved Domains (1) summary
    cl41757
    Location:1 → 355
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_017596468.3 → XP_017451957.1  cytochrome P450 20A1 isoform X1

    Conserved Domains (1) summary
    cl41757
    Location:1 → 355
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. XM_039083641.2 → XP_038939569.1  cytochrome P450 20A1 isoform X2

    Conserved Domains (1) summary
    cl41757
    Location:1 → 229
    cytochrome_P450; cytochrome P450 (CYP) superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P7D4.1 GenPept UniProtKB/Swiss-Prot:Q6P7D4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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