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Tmem131 transmembrane protein 131 [ Rattus norvegicus (Norway rat) ]

Gene ID: 316335, updated on 27-Nov-2024

Summary

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Symbol
Tmem131provided by RGD
Full Name
transmembrane protein 131provided by RGD
Primary source
RGD:1309266
See related
EnsemblRapid:ENSRNOG00000017265 AllianceGenome:RGD:1309266
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309266
Summary
Predicted to enable collagen binding activity. Predicted to be involved in collagen biosynthetic process. Predicted to be active in membrane. Orthologous to human TMEM131 (transmembrane protein 131). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 141.2), Spleen (RPKM 131.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tmem131 in Genome Data Viewer
Location:
9q21
Exon count:
43
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (46512328..46658624, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (39016470..39162841, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (43357866..43515317, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 2 open reading frame 92 Neighboring gene U4 spliceosomal RNA Neighboring gene zeta chain of T cell receptor associated protein kinase 70 Neighboring gene uncharacterized LOC134480356 Neighboring gene von Willebrand factor A domain containing 3B Neighboring gene transfer RNA alanine (anticodon AGC) 41

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables collagen binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in collagen biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transmembrane protein 131

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427652.1 → NP_001414581.1  transmembrane protein 131

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I5ZM29
    Related
    ENSRNOP00000079056.1, ENSRNOT00000112888.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    46512328..46658624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006244855.5 → XP_006244917.1  transmembrane protein 131 isoform X1

    See identical proteins and their annotated locations for XP_006244917.1

    UniProtKB/TrEMBL
    A6INF6
    Conserved Domains (2) summary
    pfam10500
    Location:1272 → 1470
    SR-25; Nuclear RNA-splicing-associated protein
    pfam12371
    Location:106 → 188
    TMEM131_like; Transmembrane protein 131-like

  2. XM_006244858.5 → XP_006244920.1  transmembrane protein 131 isoform X2

    See identical proteins and their annotated locations for XP_006244920.1

    UniProtKB/TrEMBL
    A0A8I6ACW0, A6INF6
    Related
    ENSRNOP00000090966.1, ENSRNOT00000093761.2
    Conserved Domains (2) summary
    pfam10500
    Location:1206 → 1404
    SR-25; Nuclear RNA-splicing-associated protein
    pfam12371
    Location:40 → 122
    TMEM131_like; Transmembrane protein 131-like

  3. XM_039084533.2 → XP_038940461.1  transmembrane protein 131 isoform X3

    UniProtKB/TrEMBL
    A6INF6
    Conserved Domains (1) summary
    cl13764
    Location:106 → 188
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
Nucleotide Protein Strain
Heading Accession and Version

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