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CG14443 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31595, updated on 9-Dec-2024

Summary

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Official Symbol
CG14443provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029880
Locus tag
Dmel_CG14443
See related
AllianceGenome:FB:FBgn0029880
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg14443; Dmel\CG14443
Summary
Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG14443 in Genome Data Viewer
Location:
6C2-6C2; 1-18 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6633959..6636169)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6527992..6530202)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43832 Neighboring gene Protein interacting with APP tail-1 Neighboring gene Anaphase Promoting Complex subunit 7 Neighboring gene pickled eggs Neighboring gene long non-coding RNA:CR44817 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila. Deddouche S, et al. Nat Immunol, 2008 Dec. PMID 18953338
  2. Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy. Casad ME, et al. Mol Genet Genomics, 2012 Apr. PMID 22398840, Free PMC Article
  3. The cytolinker Pigs is a direct target and a negative regulator of Notch signalling. Pines MK, et al. Development, 2010 Mar. PMID 20150280, Free PMC Article
  4. RNA silencing in the antiviral innate immune defence--role of DEAD-box RNA helicases. Ulvila J, et al. Scand J Immunol, 2010 Mar. PMID 20415780
  5. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2015 Jul 21. PMID 26199285, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14443-PB
NP_572330.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    6633959..6636169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132102.2 → NP_572330.2  uncharacterized protein Dmel_CG14443 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572330.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9W3Y5
    Conserved Domains (3) summary
    smart00487
    Location:345 → 544
    DEXDc; DEAD-like helicases superfamily
    pfam00271
    Location:560 → 670
    Helicase_C; Helicase conserved C-terminal domain
    cl21455
    Location:332 → 535
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3Y5.2 Q9W3Y5

Gene LinkOut

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