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Tmem45b transmembrane protein 45b [ Rattus norvegicus (Norway rat) ]

Gene ID: 315524, updated on 27-Nov-2024

Summary

Official Symbol
Tmem45bprovided by RGD
Official Full Name
transmembrane protein 45bprovided by RGD
Primary source
RGD:1305586
See related
EnsemblRapid:ENSRNOG00000008515 AllianceGenome:RGD:1305586
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305586
Summary
Predicted to be involved in innate immune response. Predicted to be located in Golgi apparatus; endosome membrane; and lysosomal membrane. Orthologous to human TMEM45B (transmembrane protein 45B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 50.0), Thymus (RPKM 21.8) and 9 other tissues See more
Orthologs
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Genomic context

See Tmem45b in Genome Data Viewer
Location:
8q13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (38123423..38168599, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (29865276..29910453, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (32563872..32609212, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene PR/SET domain 10 Neighboring gene ribosomal protein L32 like 1 Neighboring gene nuclear factor related to kappa B binding protein Neighboring gene uncharacterized LOC134480011 Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene S-adenosylmethionine decarboxylase 2 like, pseudogene 1 Neighboring gene phosphoribosyl pyrophosphate synthetase 1, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC124767

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033067.2NP_001028239.1  transmembrane protein 45B

    See identical proteins and their annotated locations for NP_001028239.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    Q497B2
    UniProtKB/TrEMBL
    A6JYG6
    Related
    ENSRNOP00000011329.4, ENSRNOT00000011329.6
    Conserved Domains (1) summary
    pfam04819
    Location:120237
    DUF716; Family of unknown function (DUF716)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    38123423..38168599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)