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Krt78 keratin 78 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315324, updated on 9-Dec-2024

Summary

Official Symbol
Krt78provided by RGD
Official Full Name
keratin 78provided by RGD
Primary source
RGD:1591341
See related
EnsemblRapid:ENSRNOG00000059790 AllianceGenome:RGD:1591341
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Kb40
Summary
Predicted to be active in cornified envelope. Orthologous to human KRT78 (keratin 78). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Restricted expression toward (RPKM 61.5) See more
Orthologs
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Genomic context

See Krt78 in Genome Data Viewer
Location:
7q36
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (134952877..134960727, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (133074193..133081536, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (143545245..143553063, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene keratin 4 Neighboring gene keratin 79 Neighboring gene cysteine-rich PDZ-binding protein pseudogene Neighboring gene keratin 8

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of skin epidermis IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in keratinization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cornified envelope ISO
Inferred from Sequence Orthology
more info
 
is_active_in keratin filament IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
keratin, type II cytoskeletal 78
Names
keratin 78, type II
type II keratin Kb40

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432506.1NP_001419435.1  keratin, type II cytoskeletal 78

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A0A0G2K4H7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    134952877..134960727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017595335.3XP_017450824.1  keratin, type II cytoskeletal 78

    Related
    ENSRNOP00000073048.1, ENSRNOT00000086317.3