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CG6048 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31528, updated on 4-Jan-2025

Summary

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Official Symbol
CG6048provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029827
Locus tag
Dmel_CG6048
See related
AllianceGenome:FB:FBgn0029827
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6048; SP108
Summary
Predicted to enable serine-type endopeptidase activity. Involved in regulation of terminal button organization. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG6048 in Genome Data Viewer
Location:
5C10-5C10; 1-14 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5952565..5954046)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5846598..5848079)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene female sterile (1) M3 Neighboring gene Glutamate receptor interacting protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bowman-Birk inhibitor affects pathways associated with energy metabolism in Drosophila melanogaster. Li HM, et al. Insect Mol Biol, 2010 Jun 1. PMID 20113373
  2. Genomic basis of aging and life-history evolution in Drosophila melanogaster. Remolina SC, et al. Evolution, 2012 Nov. PMID 23106705, Free PMC Article
  3. A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis. Deivasigamani S, et al. Biol Open, 2014 Oct 31. PMID 25361581, Free PMC Article
  4. A transcriptomics assessment of oxygen-temperature interactions reveals novel candidate genes underlying variation in thermal tolerance and survival. Boardman L, et al. J Insect Physiol, 2018 Apr. PMID 29038013
  5. SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis. Chaplot K, et al. Dis Model Mech, 2019 Feb 7. PMID 30635270, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 
involved_in regulation of terminal button organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG6048-PA
NP_572282.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    5952565..5954046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132054.2 → NP_572282.1  uncharacterized protein Dmel_CG6048 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572282.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W453
    Related
    FBpp0070828
    Conserved Domains (1) summary
    smart00020
    Location:45 → 284
    Tryp_SPc; Trypsin-like serine protease
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W453 Q9W453

Gene LinkOut

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