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Slc45a4 solute carrier family 45, member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315054, updated on 4-Jan-2025

Summary

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Official Symbol
Slc45a4provided by RGD
Official Full Name
solute carrier family 45, member 4provided by RGD
Primary source
RGD:1309971
See related
EnsemblRapid:ENSRNOG00000007818 AllianceGenome:RGD:1309971
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309971
Summary
Predicted to enable sucrose:proton symporter activity. Predicted to be involved in transmembrane transport. Predicted to act upstream of or within sucrose transport. Predicted to be active in membrane. Orthologous to human SLC45A4 (solute carrier family 45 member 4). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 49.0), Adrenal (RPKM 44.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc45a4 in Genome Data Viewer
Location:
7q34
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (107370826..107459163, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (105478886..105550160, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (114817817..114888998, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36 like 1 Neighboring gene DENN domain containing 3 Neighboring gene uncharacterized LOC134479924 Neighboring gene G protein-coupled receptor 20

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae. Bartölke R, et al. Biochem J, 2014 Dec 1. PMID 25164149
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables sucrose:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sucrose:proton symporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within sucrose transport ISO
Inferred from Sequence Orthology
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
solute carrier family 45 member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    107370826..107459163 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063264631.1 → XP_063120701.1  solute carrier family 45 member 4

    UniProtKB/TrEMBL
    A6HRV7, D4ADC6

  2. XM_039080226.2 → XP_038936154.1  solute carrier family 45 member 4

    UniProtKB/TrEMBL
    A6HRV7, D4ADC6
    Related
    ENSRNOP00000029754.6, ENSRNOT00000032620.8
    Conserved Domains (1) summary
    cl28910
    Location:53 → 275
    MFS; Major Facilitator Superfamily

  3. XM_006241741.5 → XP_006241803.1  solute carrier family 45 member 4

    See identical proteins and their annotated locations for XP_006241803.1

    UniProtKB/TrEMBL
    A6HRV7, D4ADC6
    Conserved Domains (1) summary
    cl28910
    Location:53 → 275
    MFS; Major Facilitator Superfamily

  4. XM_039080227.2 → XP_038936155.1  solute carrier family 45 member 4

    UniProtKB/TrEMBL
    A6HRV7, D4ADC6
    Conserved Domains (1) summary
    cl28910
    Location:53 → 275
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version

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