Atmin ATM interactor [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Atminprovided by RGD
Official Full Name: ATM interactorprovided by RGD
Primary source: RGD:1305781
See related: EnsemblRapid:ENSRNOG00000011422 AllianceGenome:RGD:1305781
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Asciz; RGD1305781
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; dynein complex binding activity; and transcription cis-regulatory region binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within motile cilium assembly; positive regulation of gene expression; and positive regulation of non-motile cilium assembly. Predicted to be located in nuclear body. Orthologous to human ATMIN (ATM interactor). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 50.6), Thymus (RPKM 35.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (61905343..61922443)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (44996506..45013606)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (49482482..49499682)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH133499 (e-PCR)
- UniSTS:216782

NoName (e-PCR)
- UniSTS:236013

NoName (e-PCR)
- UniSTS:236014

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables dynein complex binding	ISO Inferred from Sequence Orthology more info
enables transcription cis-regulatory region binding	IBA Inferred from Biological aspect of Ancestor more info
enables transcription cis-regulatory region binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within motile cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of gene expression	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of non-motile cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nuclear body	IEA Inferred from Electronic Annotation more info
located_in nuclear body	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ATM interactor

Names: ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191786.2 → NP_001178715.1 ATM interactor

Status: VALIDATED

Source sequence(s)

BC105857, JAXUCZ010000019

UniProtKB/TrEMBL

F1LN81

Related

ENSRNOP00000015180.8, ENSRNOT00000015180.9

Conserved Domains (1) summary

sd00017
Location:129 → 156

ZF_C2H2; C2H2 Zn finger [structural motif]