NAAT1 Nutrient Amino Acid Transporter 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: NAAT1provided by FlyBase
Official Full Name: Nutrient Amino Acid Transporter 1provided by FlyBase
Primary source: FLYBASE:FBgn0029762
Locus tag: Dmel_CG3252
See related: AllianceGenome:FB:FBgn0029762
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0149848.3; CG3252; Dmel\CG3252; dmNAT1; DmNAT1; Naat1
Summary: Enables amino acid transmembrane transporter activity. Involved in carboxylic acid transport; neutral amino acid transport; and sodium ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior-posterior subdivision of organism; embryonic/larval salivary gland; epithelial tube; ganglia; and gut section. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (5405238..5410849, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (5299271..5304882, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables D-amino acid transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables L-amino acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-amino acid transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables amino acid:monoatomic cation symporter activity	ISM Inferred from Sequence Model more info	PubMed
enables amino acid:sodium symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables amino acid:sodium symporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables neurotransmitter transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables neutral L-amino acid transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in D-amino acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in L-amino acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in amino acid transmembrane transport	ISM Inferred from Sequence Model more info	PubMed
involved_in glycine import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in neurotransmitter transport	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in neutral amino acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in sodium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in sodium ion transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISM Inferred from Sequence Model more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IC Inferred by Curator more info	PubMed

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