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Wdr20 WD repeat domain 20 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314453, updated on 4-Jan-2025

Summary

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Official Symbol
Wdr20provided by RGD
Official Full Name
WD repeat domain 20provided by RGD
Primary source
RGD:1306499
See related
EnsemblRapid:ENSRNOG00000007333 AllianceGenome:RGD:1306499
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Wdr20a
Summary
Predicted to enable deubiquitinase activator activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human WDR20 (WD repeat domain 20). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 54.8), Kidney (RPKM 54.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Wdr20 in Genome Data Viewer
Location:
6q32
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (135572502..135642688)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (129751952..129821464)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (135156984..135226425)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549239 Neighboring gene heat shock protein 90 alpha family class A member 1 Neighboring gene ribosomal protein L35A like 2 Neighboring gene MOK protein kinase Neighboring gene uncharacterized LOC108351302 Neighboring gene transfer RNA isoleucine (anticodon AAU) 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables deubiquitinase activator activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
WD repeat-containing protein 20
Names
WD repeat domain 20a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100894.1 → NP_001094364.1  WD repeat-containing protein 20

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0, D3ZVJ9
    Related
    ENSRNOP00000009709.5, ENSRNOT00000009709.9
    Conserved Domains (3) summary
    COG2319
    Location:147 → 435
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:152 → 196
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:149 → 314
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    135572502..135642688
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039112414.2 → XP_038968342.1  WD repeat-containing protein 20 isoform X15

    UniProtKB/TrEMBL
    A0A8I6AK72

  2. XM_063262014.1 → XP_063118084.1  WD repeat-containing protein 20 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  3. XM_017594187.3 → XP_017449676.1  WD repeat-containing protein 20 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0
    Conserved Domains (2) summary
    sd00039
    Location:226 → 270
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:223 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_017594186.3 → XP_017449675.1  WD repeat-containing protein 20 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0
    Conserved Domains (2) summary
    sd00039
    Location:226 → 270
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:223 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_039112410.2 → XP_038968338.1  WD repeat-containing protein 20 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0
    Conserved Domains (2) summary
    sd00039
    Location:226 → 270
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:223 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_039112411.2 → XP_038968339.1  WD repeat-containing protein 20 isoform X5

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0
    Related
    ENSRNOP00000087682.2, ENSRNOT00000114885.2
    Conserved Domains (2) summary
    sd00039
    Location:226 → 270
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:223 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  7. XM_063262015.1 → XP_063118085.1  WD repeat-containing protein 20 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  8. XM_017594188.3 → XP_017449677.1  WD repeat-containing protein 20 isoform X4

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  9. XM_063262016.1 → XP_063118086.1  WD repeat-containing protein 20 isoform X6

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  10. XM_063262021.1 → XP_063118091.1  WD repeat-containing protein 20 isoform X12

    UniProtKB/TrEMBL
    A0A8I6G8P3

  11. XM_063262017.1 → XP_063118087.1  WD repeat-containing protein 20 isoform X7

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  12. XM_063262018.1 → XP_063118088.1  WD repeat-containing protein 20 isoform X8

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  13. XM_063262020.1 → XP_063118090.1  WD repeat-containing protein 20 isoform X11

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  14. XM_063262022.1 → XP_063118092.1  WD repeat-containing protein 20 isoform X14

    UniProtKB/TrEMBL
    A0A8I6G8P3

  15. XM_006240586.5 → XP_006240648.1  WD repeat-containing protein 20 isoform X13

    UniProtKB/TrEMBL
    A0A8I6G8P3
    Conserved Domains (3) summary
    COG2319
    Location:78 → 374
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:91 → 135
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:88 → 253
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  16. XM_063262019.1 → XP_063118089.1  WD repeat-containing protein 20 isoform X9

    UniProtKB/TrEMBL
    A0A0G2K2B7, A6KBN0

  17. XM_063262023.1 → XP_063118093.1  WD repeat-containing protein 20 isoform X17

    UniProtKB/TrEMBL
    A0A8I6A274

  18. XM_008764935.4 → XP_008763157.1  WD repeat-containing protein 20 isoform X16

    See identical proteins and their annotated locations for XP_008763157.1

    UniProtKB/TrEMBL
    A0A8I5ZK85, A0A8I6A274
    Related
    ENSRNOP00000083213.2, ENSRNOT00000118053.2

  19. XM_006240583.5 → XP_006240645.1  WD repeat-containing protein 20 isoform X10

    UniProtKB/TrEMBL
    A0A0G2K2B7, A0A8I6A891, A6KBN0
    Related
    ENSRNOP00000072178.3, ENSRNOT00000082595.3
    Conserved Domains (3) summary
    COG2319
    Location:147 → 435
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:152 → 196
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:149 → 314
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  20. XM_039112415.2 → XP_038968343.1  WD repeat-containing protein 20 isoform X18

    UniProtKB/TrEMBL
    A0A8I6A274

RNA

  1. XR_005505530.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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