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Fam161b FAM161 centrosomal protein B [ Rattus norvegicus (Norway rat) ]

Gene ID: 314311, updated on 9-Dec-2024

Summary

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Official Symbol
Fam161bprovided by RGD
Official Full Name
FAM161 centrosomal protein Bprovided by RGD
Primary source
RGD:1309058
See related
EnsemblRapid:ENSRNOG00000011112 AllianceGenome:RGD:1309058
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309058
Summary
Predicted to be involved in cilium organization. Predicted to be located in cytoplasmic microtubule. Predicted to colocalize with cilium. Orthologous to human FAM161B (FAM161 centrosomal protein B). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Testes (RPKM 48.4), Muscle (RPKM 39.2) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam161b in Genome Data Viewer
Location:
6q31
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (109722073..109750003, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (103990603..104007754, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (108060019..108076303, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene prostaglandin reductase 2 Neighboring gene zinc finger protein 410 Neighboring gene coenzyme Q6 monooxygenase Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 Neighboring gene basal body orientation factor 1 Neighboring gene ring finger protein 113A2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The retinitis pigmentosa 28 protein FAM161A is a novel ciliary protein involved in intermolecular protein interaction and microtubule association. Zach F, et al. Hum Mol Genet, 2012 Nov 1. PMID 22791751
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
colocalizes_with cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
  
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
FAM161 centrosomal protein B; protein FAM161B
Names
FAM161B, centrosomal protein
family with sequence similarity 161, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431915.1 → NP_001418844.1  FAM161 centrosomal protein B isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6AGZ6, A6JDV3

  2. NM_001431916.1 → NP_001418845.1  FAM161 centrosomal protein B isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6AGZ6, A6JDV3

  3. NM_001431917.1 → NP_001418846.1  FAM161 centrosomal protein B isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6JDV3, D4A7T7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    109722073..109750003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056985583.2 → XP_056841563.1  protein FAM161B isoform X3

    Related
    ENSRNOP00000110477.1, ENSRNOT00000172365.1

  2. XM_063262683.1 → XP_063118753.1  protein FAM161B isoform X4

    Related
    ENSRNOP00000014814.6, ENSRNOT00000014814.8

  3. XM_056985582.2 → XP_056841562.1  protein FAM161B isoform X3

  4. XM_063262682.1 → XP_063118752.1  protein FAM161B isoform X2

    UniProtKB/TrEMBL
    A6JDV3

  5. XM_063262681.1 → XP_063118751.1  protein FAM161B isoform X1

    UniProtKB/TrEMBL
    A6JDV3
Nucleotide Protein Strain
Heading Accession and Version

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