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Zfp410 zinc finger protein 410 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314310, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp410provided by RGD
Official Full Name
zinc finger protein 410provided by RGD
Primary source
RGD:1305636
See related
EnsemblRapid:ENSRNOG00000010985 AllianceGenome:RGD:1305636
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf410
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of gene expression and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF410 (zinc finger protein 410). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 142.0), Kidney (RPKM 89.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp410 in Genome Data Viewer
Location:
6q31
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (109695223..109721369)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (103963265..103990252)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (108031747..108058836)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479232 Neighboring gene prostaglandin reductase 2 Neighboring gene FAM161 centrosomal protein B Neighboring gene coenzyme Q6 monooxygenase Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 Neighboring gene basal body orientation factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 410

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108042.3 → NP_001101512.1  zinc finger protein 410

    See identical proteins and their annotated locations for NP_001101512.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6A1H7, A6JDU7, B4F792, F7FMS9
    Conserved Domains (3) summary
    COG5048
    Location:228 → 368
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:281 → 303
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:325 → 350
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001433978.1 → NP_001420907.1  zinc finger protein 410

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

  3. NM_001433979.1 → NP_001420908.1  zinc finger protein 410

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

RNA

  1. NR_197622.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    109695223..109721369
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261938.1 → XP_063118008.1  zinc finger protein 410 isoform X1

  2. XM_063261939.1 → XP_063118009.1  zinc finger protein 410 isoform X2

    UniProtKB/TrEMBL
    A6JDU7, B4F792, F7FMS9

  3. XM_063261937.1 → XP_063118007.1  zinc finger protein 410 isoform X1

  4. XM_006240338.3 → XP_006240400.1  zinc finger protein 410 isoform X2

    UniProtKB/TrEMBL
    A0A8I6A1H7, A6JDU7, B4F792, F7FMS9
    Related
    ENSRNOP00000014738.5, ENSRNOT00000014738.7
    Conserved Domains (3) summary
    COG5048
    Location:228 → 368
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:281 → 303
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:325 → 350
    zf-H2C2_2; Zinc-finger double domain

  5. XM_063261936.1 → XP_063118006.1  zinc finger protein 410 isoform X1

RNA

  1. XR_005505524.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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