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Pp2C1 - Protein phosphatase 2C

Predicted to enable mitogen-activated protein kinase binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of gene expression, epigenetic and regulation of intracellular signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa