Fdx2 ferredoxin 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fdx2provided by RGD
Official Full Name: ferredoxin 2provided by RGD
Primary source: RGD:1561264
See related: EnsemblRapid:ENSRNOG00000023020 AllianceGenome:RGD:1561264
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fdx1l; RGD1561264
Summary: Predicted to enable electron transfer activity. Predicted to be involved in [2Fe-2S] cluster assembly and electron transport chain. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Muscle (RPKM 123.1), Brain (RPKM 120.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q13

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (27881091..27886230, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (19604916..19609832, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (22086534..22091450, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:236065 (e-PCR)
- UniSTS:236065

RH128477 (e-PCR)
- UniSTS:211785

BE106681 (e-PCR)
- UniSTS:246363

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 2 iron, 2 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables electron transfer activity	IBA Inferred from Biological aspect of Ancestor more info
enables electron transfer activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in P450-containing electron transport chain	IEA Inferred from Electronic Annotation more info
involved_in [2Fe-2S] cluster assembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of [4Fe-4S] cluster assembly	ISO Inferred from Sequence Orthology more info
involved_in electron transport chain	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed

General protein information

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Preferred Names: ferredoxin-2, mitochondrial

Names: adrenodoxin-like protein, mitochondrial; ferredoxin 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.