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Utp11 UTP11, small subunit processome component [ Rattus norvegicus (Norway rat) ]

Gene ID: 313581, updated on 27-Nov-2024

Summary

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Official Symbol
Utp11provided by RGD
Official Full Name
UTP11, small subunit processome componentprovided by RGD
Primary source
RGD:621412
See related
EnsemblRapid:ENSRNOG00000007174 AllianceGenome:RGD:621412
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Cgi94; Cgi-94; Utp11l; RGD1559610
Summary
Predicted to be involved in nervous system development; positive regulation of apoptotic process; and ribosomal small subunit biogenesis. Predicted to be located in cytoplasm and extracellular space. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP11 (UTP11 small subunit processome component). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 160.5), Thymus (RPKM 145.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Utp11 in Genome Data Viewer
Location:
5q36
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (142215974..142230859, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (136931279..136946164, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (142666288..142681173, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102548116 Neighboring gene POU class 3 homeobox 1 Neighboring gene U6 spliceosomal RNA Neighboring gene four and a half LIM domains 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain. Heese K, et al. Eur J Neurosci, 2002 Jan. PMID 11860508
  2. Comparative gene identification-94--a pivotal regulator of apoptosis. Heese K, et al. Neuroscience, 2003. PMID 12559088
  3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
  
involved_in nervous system development ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal small subunit biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
probable U3 small nucleolar RNA-associated protein 11
Names
U3 snoRNA-associated protein 11
UTP11, small subunit processome component homolog
UTP11-like, U3 small nucleolar ribonucleoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107978.2 → NP_001101448.1  probable U3 small nucleolar RNA-associated protein 11

    See identical proteins and their annotated locations for NP_001101448.1

    Status: PROVISIONAL

    Source sequence(s)
    BC168964
    UniProtKB/TrEMBL
    A0A8I5ZYE3, A6IS47, B5DF84, F7EN70
    Related
    ENSRNOP00000009882.4, ENSRNOT00000009882.7
    Conserved Domains (1) summary
    pfam03998
    Location:13 → 253
    Utp11; Utp11 protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    142215974..142230859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_130825.1: Suppressed sequence

    Description
    NM_130825.1: This RefSeq was permanently suppressed because it was based on a sequence from a different organism.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8R5K5.1 GenPept UniProtKB/Swiss-Prot:Q8R5K5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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