U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313373, updated on 27-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Cyp2j10provided by RGD
Official Full Name
cytochrome P450, family 2, subfamily j, polypeptide 10provided by RGD
Primary source
RGD:1563215
See related
EnsemblRapid:ENSRNOG00000042224 AllianceGenome:RGD:1563215
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563215
Summary
Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension; myocardial infarction; pulmonary hypertension; renal fibrosis; and renal hypertension. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 46.1), Liver (RPKM 28.1) and 8 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Cyp2j10 in Genome Data Viewer
Location:
5q33
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (116076012..116110914, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (110960319..110995220, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (115067847..115101961, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120102925 Neighboring gene hook microtubule-tethering protein 1 Neighboring gene cytochrome P450 2J3-like Neighboring gene cytochrome P450, family 2, subfamily j, polypeptide 16, pseudogene 1 Neighboring gene uncharacterized LOC134479009 Neighboring gene cytochrome P450, family 2, subfamily j, polypeptide 16

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC188856

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
cytochrome P450, family 2, subfamily j, polypeptide 10

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134980.2 → NP_001128452.2  cytochrome P450, family 2, subfamily j, polypeptide 10

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    B5DEP8, E9PSJ0
    Related
    ENSRNOP00000046904.6, ENSRNOT00000045686.7
    Conserved Domains (1) summary
    cl41757
    Location:75 → 496
    cytochrome_P450; cytochrome P450 (CYP) superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    116076012..116110914 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039109899.2 → XP_038965827.1  cytochrome P450, family 2, subfamily j, polypeptide 10 isoform X1

    UniProtKB/TrEMBL
    A6JRI7
    Conserved Domains (1) summary
    cl41757
    Location:75 → 398
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_039109900.2 → XP_038965828.1  cytochrome P450, family 2, subfamily j, polypeptide 10 isoform X3

    Conserved Domains (2) summary
    cl12078
    Location:18 → 118
    p450; Cytochrome P450
    cl41757
    Location:75 → 289
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. XM_063287640.1 → XP_063143710.1  cytochrome P450, family 2, subfamily j, polypeptide 10 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools