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Slc25a51 solute carrier family 25, member 51 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313241, updated on 27-Nov-2024

Summary

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Official Symbol
Slc25a51provided by RGD
Official Full Name
solute carrier family 25, member 51provided by RGD
Primary source
RGD:1305190
See related
EnsemblRapid:ENSRNOG00000039278 AllianceGenome:RGD:1305190
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mcart1
Summary
Predicted to enable NAD transmembrane transporter activity. Predicted to be involved in aerobic electron transport chain and mitochondrial NAD transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Orthologous to human SLC25A51 (solute carrier family 25 member 51) and SLC25A52 (solute carrier family 25 member 52). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 317.7), Adrenal (RPKM 210.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc25a51 in Genome Data Viewer
Location:
5q22
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (64445610..64459172, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (59649980..59663454, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (60942566..60956135, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene phosphoglycerate mutase 1, pseudogene 8 Neighboring gene DDB1 and CUL4 associated factor 10 like Neighboring gene DDB1 and CUL4 associated factor 10 Neighboring gene SH2 domain containing adaptor protein B Neighboring gene uncharacterized LOC103692348

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables NAD transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NAD transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables NAD transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of aerobic electron transport chain ISO
Inferred from Sequence Orthology
more info
  
involved_in aerobic electron transport chain ISO
Inferred from Sequence Orthology
more info
  
involved_in aerobic electron transport chain ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in mitochondrial NAD transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial NAD transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in mitochondrial NAD transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51
Names
mitochondrial NAD(+) transporter SLC25A51
mitochondrial carrier triple repeat 1
mitochondrial carrier triple repeat protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024785.3 → NP_001019956.1  mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

    See identical proteins and their annotated locations for NP_001019956.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/Swiss-Prot
    Q52KK3
    UniProtKB/TrEMBL
    A0A8I5YBE2, A6IJ96
    Related
    ENSRNOP00000056892.2, ENSRNOT00000060149.6
    Conserved Domains (1) summary
    pfam00153
    Location:31 → 112
    Mito_carr; Mitochondrial carrier protein

  2. NM_001394297.1 → NP_001381226.1  mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/Swiss-Prot
    Q52KK3
    UniProtKB/TrEMBL
    A0A8I5YBE2, A6IJ96
    Related
    ENSRNOP00000065025.1, ENSRNOT00000071116.4
    Conserved Domains (1) summary
    pfam00153
    Location:31 → 112
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    64445610..64459172 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006238065.5 → XP_006238127.1  mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 isoform X1

    See identical proteins and their annotated locations for XP_006238127.1

    UniProtKB/Swiss-Prot
    Q52KK3
    UniProtKB/TrEMBL
    A0A8I5YBE2, A6IJ96
    Conserved Domains (1) summary
    pfam00153
    Location:31 → 112
    Mito_carr; Mitochondrial carrier protein

  2. XM_063287630.1 → XP_063143700.1  mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 isoform X1

    UniProtKB/Swiss-Prot
    Q52KK3
    UniProtKB/TrEMBL
    A6IJ96
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q52KK3.1 GenPept UniProtKB/Swiss-Prot:Q52KK3

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials