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CG2681 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31258, updated on 2-Nov-2024

Summary

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Official Symbol
CG2681provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0024997
Locus tag
Dmel_CG2681
See related
AllianceGenome:FB:FBgn0024997
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
100G10.2; Dmel\CG2681; EG:100G10.2
Summary
Predicted to enable ubiquitin conjugating enzyme binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG2681 in Genome Data Viewer
Location:
3B2-3B3; 1-1.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2708684..2711668)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2602717..2605701)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene UDP-galactose transporter Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hitchhiking mapping: a population-based fine-mapping strategy for adaptive mutations in Drosophilamelanogaster. Harr B, et al. Proc Natl Acad Sci U S A, 2002 Oct 1. PMID 12351680, Free PMC Article
  2. Linkage disequilibrium patterns across a recombination gradient in African Drosophila melanogaster. Andolfatto P, et al. Genetics, 2003 Nov. PMID 14668383, Free PMC Article
  3. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article
  4. Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat. Napoletano F, et al. EMBO J, 2011 Mar 2. PMID 21278706, Free PMC Article
  5. From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. Benos PV, et al. Genome Res, 2001 May. PMID 11337470, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2681-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2708684..2711668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130666.2 → NP_570022.2  uncharacterized protein Dmel_CG2681 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_570022.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W4W4
    Related
    FBpp0070458, FBtr0070480
    Conserved Domains (2) summary
    cd00162
    Location:206 → 244
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam03145
    Location:248 → 442
    Sina; Seven in absentia protein family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O76862 O76862
Q8IH73 Q8IH73
Q8MM55 Q8MM55
Q8MM56 Q8MM56
Q8MTX7 Q8MTX7
Q8MTX8 Q8MTX8
Q9W4W4 Q9W4W4

Gene LinkOut

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