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temp tempura [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31212, updated on 9-Dec-2024

Summary

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Official Symbol
tempprovided by FlyBase
Official Full Name
tempuraprovided by FlyBase
Primary source
FLYBASE:FBgn0027296
Locus tag
Dmel_CG3073
See related
AllianceGenome:FB:FBgn0027296
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3073; Dmel\CG3073; l(1)G0144
Summary
Contributes to Rab geranylgeranyltransferase activity. Involved in sensory organ development. Located in cytoplasm. Part of Rab-protein geranylgeranyltransferase complex. Is expressed in external sensory organ precursor cell and organism. Orthologous to human PTAR1 (protein prenyltransferase alpha subunit repeat containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See temp in Genome Data Viewer
Location:
2F2-2F2; 1-0.9 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2260207..2262515, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2154240..2156548, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45480

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deep-fried signaling: tempura gets notch cooking. Sedwick C. PLoS Biol, 2014 Jan. PMID 24492884, Free PMC Article
  2. Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11. Charng WL, et al. PLoS Biol, 2014 Jan. PMID 24492843, Free PMC Article
  3. Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases. Salazar JL, et al. Adv Exp Med Biol, 2018. PMID 30030826, Free PMC Article
  4. A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease. Graves HK, et al. G3 (Bethesda), 2020 Jan 7. PMID 31767637, Free PMC Article
  5. Neutral Competition for Drosophila Follicle and Cyst Stem Cell Niches Requires Vesicle Trafficking Genes. Cook MS, et al. Genetics, 2017 Jul. PMID 28512187, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Drosophila Tempura, a novel protein prenyltransferase alpha subunit, regulates notch signaling via Rab1 and Rab11.
    Title: Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to Rab geranylgeranyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to Rab geranylgeranyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein prenyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein prenylation IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory organ development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Rab-protein geranylgeranyltransferase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
tempura
Names
CG3073-PA
CG3073-PB
lethal (1) G0144
temp-PA
temp-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2260207..2262515 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130636.3 → NP_569992.1  tempura, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569992.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W501
    Related
    FBpp0070398
    Conserved Domains (1) summary
    pfam01239
    Location:168 → 195
    PPTA; Protein prenyltransferase alpha subunit repeat

  2. NM_001297889.1 → NP_001284818.1  tempura, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284818.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W501
    Conserved Domains (1) summary
    pfam01239
    Location:168 → 195
    PPTA; Protein prenyltransferase alpha subunit repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W501 Q9W501

Gene LinkOut

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