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Ninl ninein-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 311529, updated on 4-Jan-2025

Summary

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Official Symbol
Ninlprovided by RGD
Official Full Name
ninein-likeprovided by RGD
Primary source
RGD:1306152
See related
EnsemblRapid:ENSRNOG00000027747 AllianceGenome:RGD:1306152
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nlp; RGD1306152
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in microtubule anchoring at centrosome. Predicted to be located in cytoplasm. Predicted to be active in centrosome. Orthologous to human NINL (ninein like). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 94.1), Testes (RPKM 71.9) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ninl in Genome Data Viewer
Location:
3q41
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (160208757..160275077, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (139748353..139814683, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (146719210..146785450, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene GINS complex subunit 1 Neighboring gene activator of basal transcription 1, pseudogene 2 Neighboring gene RNA, U6 small nuclear 722 Neighboring gene uncharacterized LOC134486182 Neighboring gene uncharacterized LOC134486183 Neighboring gene N-acetylneuraminic acid phosphatase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in microtubule anchoring at centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ninein-like; ninein-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430466.1 → NP_001417395.1  ninein-like

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A0A8I6A2X1, D4A5N1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    160208757..160275077 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008762394.4 → XP_008760616.2  ninein-like protein isoform X2

    Related
    ENSRNOP00000101786.1, ENSRNOT00000166583.1
    Conserved Domains (3) summary
    COG1196
    Location:1058 → 1387
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:462 → 1340
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13499
    Location:199 → 260
    EF-hand_7; EF-hand domain pair

  2. XM_039106651.2 → XP_038962579.1  ninein-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8I6A2X1, A0A8I6A773
    Related
    ENSRNOP00000088771.1, ENSRNOT00000116558.2
    Conserved Domains (3) summary
    COG1196
    Location:1096 → 1425
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:340 → 913
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13499
    Location:199 → 260
    EF-hand_7; EF-hand domain pair

  3. XM_063285077.1 → XP_063141147.1  ninein-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I6A2X1
    Related
    ENSRNOP00000100824.1, ENSRNOT00000163129.1

  4. XM_039106654.2 → XP_038962582.1  ninein-like protein isoform X4

    UniProtKB/TrEMBL
    A0A8I6A2X1
    Related
    ENSRNOP00000061689.4, ENSRNOT00000068689.5
    Conserved Domains (3) summary
    COG1196
    Location:1041 → 1370
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:291 → 858
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13499
    Location:199 → 260
    EF-hand_7; EF-hand domain pair

  5. XM_039106653.2 → XP_038962581.1  ninein-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8I6A2X1, A0A8I6A773
    Conserved Domains (3) summary
    COG1196
    Location:1096 → 1425
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:340 → 913
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13499
    Location:199 → 260
    EF-hand_7; EF-hand domain pair

  6. XM_063285079.1 → XP_063141149.1  ninein-like protein isoform X6

    UniProtKB/TrEMBL
    A6KHH5

  7. XM_039106657.2 → XP_038962585.1  ninein-like protein isoform X5

    Conserved Domains (4) summary
    PRK13589
    Location:27 → 85
    PRK13589; flagellin A
    PHA03378
    Location:647 → 811
    PHA03378; EBNA-3B; Provisional
    COG1196
    Location:824 → 1115
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:68 → 641
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein Strain
Heading Accession and Version

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