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Vps26 - Vacuolar protein sorting 26

Enables cargo receptor activity. Involved in endosome to plasma membrane protein transport and regulation of Wnt signaling pathway. Part of retromer complex. Is expressed in adult head; adult heart; and photoreceptor neurons. Used to study brain cancer. Human ortholog(s) of this gene implicated in diabetic retinopathy and type 2 diabetes mellitus. Orthologous to several human genes including VPS26B (VPS26 retromer complex component B). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Vps26

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Species Gene Architecture aa