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Pex5 - Peroxin 5

Predicted to enable peroxisome matrix targeting signal-1 binding activity. Involved in protein import into peroxisome matrix and response to anesthetic. Located in cytosol and peroxisome. Is expressed in embryonic cortex and yolk. Used to study peroxisomal biogenesis disorder and peroxisome biogenesis disorder 2A. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to several human genes including PEX5 (peroxisomal biogenesis factor 5). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa