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inc - insomniac

Enables myosin binding activity and protein homodimerization activity. Involved in regulation of circadian sleep/wake cycle, sleep and sleep. Acts upstream of with a positive effect on retrograde trans-synaptic signaling. Is active in postsynaptic cytosol. Is expressed in several structures, including adult brain; adult head; adult mushroom body; adult pars intercerebralis; and fan-shaped body. Human ortholog(s) of this gene implicated in myoclonic dystonia 26. Orthologous to several human genes including KCTD2 (potassium channel tetramerization domain containing 2) and KCTD5 (potassium channel tetramerization domain containing 5). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa