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TfIIA-S-2 TfIIA-S-2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31048, updated on 9-Dec-2024

Summary

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Official Symbol
TfIIA-S-2provided by FlyBase
Official Full Name
TfIIA-S-2provided by FlyBase
Primary source
FLYBASE:FBgn0040338
Locus tag
Dmel_CG11639
See related
AllianceGenome:FB:FBgn0040338
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11639; Dmel\CG11639; EG:BACR7A4.7; TFIIA; tfiia-s-2; TFIIA-S-2
Summary
Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be part of transcription factor TFIIA complex. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See TfIIA-S-2 in Genome Data Viewer
Location:
1E1-1E1; 1-0.1 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (1011101..1011643, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (905134..905676, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45476 Neighboring gene uncharacterized protein Neighboring gene suppressor of white-apricot Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biology's name game. Pearson H. Nature, 2001 Jun 7. PMID 11395736
  2. Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome. Ni X, et al. PLoS Biol, 2012. PMID 23139640, Free PMC Article
  3. Alignment and quantification of ChIP-exo crosslinking patterns reveal the spatial organization of protein-DNA complexes. Yamada N, et al. Nucleic Acids Res, 2020 Nov 18. PMID 32747934, Free PMC Article
  4. Paused RNA polymerase II inhibits new transcriptional initiation. Shao W, et al. Nat Genet, 2017 Jul. PMID 28504701
  5. ATP-dependent nucleosome remodeling and histone hyperacetylation synergistically facilitate transcription of chromatin. Mizuguchi G, et al. J Biol Chem, 2001 May 4. PMID 11279013

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables TBP-class protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in RNA polymerase II preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation at RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription initiation at RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of transcription factor TFIIA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIIA complex IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIIA complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
TfIIA-S-2
Names
CG11639-PA
TfIIA-S-2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    1011101..1011643 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130521.1 → NP_569877.1  TfIIA-S-2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569877.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DMX0, D3DMX1, Q9W5B9
    UniProtKB/TrEMBL
    H0RNC2
    Related
    FBpp0070177, FBtr0070184
    Conserved Domains (3) summary
    cd10145
    Location:2 → 50
    TFIIA_gamma_N; Gamma subunit of transcription initiation factor IIA, N-terminal helical domain
    COG5123
    Location:3 → 103
    TOA2; Transcription initiation factor IIA, gamma subunit [Transcription]
    pfam02751
    Location:53 → 99
    TFIIA_gamma_C; Transcription initiation factor IIA, gamma subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W5B9.1 Q9W5B9

Gene LinkOut

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