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CG3703 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31045, updated on 4-Jan-2025

Summary

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Official Symbol
CG3703provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0040348
Locus tag
Dmel_CG3703
See related
AllianceGenome:FB:FBgn0040348
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BACR7A4.15; Dmel\CG3703; EG:BACR7A4.15
Summary
Predicted to enable GTPase activator activity. Predicted to be involved in intracellular protein transport. Predicted to be active in cytoplasm. Is expressed in embryonic brain; embryonic head sensory system; and larval ventral nerve cord. Orthologous to human RUNDC1 (RUN domain containing 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG3703 in Genome Data Viewer
Location:
1D2-1D2; 1-0 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (942474..945773, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (836507..839806, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene TRAM Neighboring gene uncharacterized protein Neighboring gene mus81 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Template disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutants. Johnson-Schlitz D, et al. Proc Natl Acad Sci U S A, 2006 Nov 7. PMID 17075047, Free PMC Article
  2. The endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis. Lim DH, et al. FEBS Lett, 2011 Oct 3. PMID 21889502
  3. Rab2 drives axonal transport of dense core vesicles and lysosomal organelles. Lund VK, et al. Cell Rep, 2021 Apr 13. PMID 33852866
  4. Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. Page AR, et al. EMBO J, 2005 Dec 21. PMID 16369566, Free PMC Article
  5. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3703-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    942474..945773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130518.3 → NP_569874.1  uncharacterized protein Dmel_CG3703 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569874.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NF74, Q9W5C1
    Related
    FBpp0070180
    Conserved Domains (1) summary
    pfam02759
    Location:516 → 703
    RUN; RUN domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9NF74 Q9NF74
Q9W5C1 Q9W5C1

Gene LinkOut

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