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Mrpl49 mitochondrial ribosomal protein L49 [ Rattus norvegicus (Norway rat) ]

Gene ID: 309176, updated on 27-Nov-2024

Summary

Official Symbol
Mrpl49provided by RGD
Official Full Name
mitochondrial ribosomal protein L49provided by RGD
Primary source
RGD:1309920
See related
AllianceGenome:RGD:1309920
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Aa2-277
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL49 (mitochondrial ribosomal protein L49). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 274.3), Brain (RPKM 233.5) and 9 other tissues See more
Orthologs
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Genomic context

See Mrpl49 in Genome Data Viewer
Location:
1q43
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212775357..212779364, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (203346068..203350040, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (221417336..221420115, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 20 Neighboring gene calpain 1 Neighboring gene uncharacterized LOC108349685 Neighboring gene synoviolin 1 Neighboring gene zinc finger, HIT-type containing 2 Neighboring gene FAU ubiquitin like and ribosomal protein S30 fusion

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
large ribosomal subunit protein mL49
Names
39S ribosomal protein L49, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001047883.2NP_001041348.1  large ribosomal subunit protein mL49

    See identical proteins and their annotated locations for NP_001041348.1

    Status: VALIDATED

    Source sequence(s)
    FM121128, JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I6AG94, A6HZC2, Q7TP77
    Conserved Domains (1) summary
    pfam05046
    Location:82161
    Img2; Mitochondrial large subunit ribosomal protein (Img2)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    212775357..212779364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063264399.1XP_063120469.1  large ribosomal subunit protein mL49 isoform X1