Sec23ip SEC23 interacting protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Sec23ipprovided by RGD
Official Full Name: SEC23 interacting proteinprovided by RGD
Primary source: RGD:1309328
See related: EnsemblRapid:ENSRNOG00000020411 AllianceGenome:RGD:1309328
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable phospholipase activity. Predicted to act upstream of or within acrosome assembly and single fertilization. Predicted to be located in cis-Golgi network; endoplasmic reticulum exit site; and perinuclear endoplasmic reticulum. Predicted to be active in COPII-coated ER to Golgi transport vesicle. Orthologous to human SEC23IP (SEC23 interacting protein). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Spleen (RPKM 99.6), Thymus (RPKM 97.0) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 1q37

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (192751379..192794345)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (183320950..183363944)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (200167075..200210362)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

BI286725 (e-PCR)
- UniSTS:245417

BE098390 (e-PCR)
- UniSTS:245235

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phospholipase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within acrosome assembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within single fertilization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within spermatid development	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in COPII-coated ER to Golgi transport vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in cis-Golgi network	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum exit site	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in perinuclear endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: SEC23-interacting protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001134859.1 → NP_001128331.1 SEC23-interacting protein

See identical proteins and their annotated locations for NP_001128331.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

A6IA18, A6IA19, G3V8Q8

Related

ENSRNOP00000027665.4, ENSRNOT00000027665.8

Conserved Domains (3) summary

smart00454
Location:650 → 701

SAM; Sterile alpha motif

pfam02862
Location:781 → 987

DDHD; DDHD domain

cl15755
Location:635 → 703

SAM_superfamily; SAM (Sterile alpha motif )

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

192751379..192794345

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006230387.4 → XP_006230449.1 SEC23-interacting protein isoform X1

UniProtKB/TrEMBL

A6IA18

Conserved Domains (3) summary

smart00454
Location:650 → 701

SAM; Sterile alpha motif

pfam02862
Location:781 → 986

DDHD; DDHD domain

cl15755
Location:635 → 703

SAM_superfamily; SAM (Sterile alpha motif )

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001037779.1: Suppressed sequence

Description

NM_001037779.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.