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Zfp819 zinc finger protein 819 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308561, updated on 4-Jan-2025

Summary

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Official Symbol
Zfp819provided by RGD
Official Full Name
zinc finger protein 819provided by RGD
Primary source
RGD:1309564
See related
EnsemblRapid:ENSRNOG00000022701 EnsemblRapid:ENSRNOG00000030160 AllianceGenome:RGD:1309564
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309564
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF175 (zinc finger protein 175). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Testes (RPKM 40.5), Kidney (RPKM 21.6) and 9 other tissues See more
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Genomic context

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See Zfp819 in Genome Data Viewer
Location:
1q22
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (103163570..103222203)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (94027347..94048767)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (99521177..99539232)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 658 Neighboring gene zinc finger protein 719 Neighboring gene uncharacterized LOC120099801 Neighboring gene CEA cell adhesion molecule 18 Neighboring gene sialic acid binding Ig-like lectin 8 Neighboring gene cytosolic thiouridylase subunit 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification and characterization of reproductive KRAB-ZF genes in mice. Jin S, et al. Gene, 2015 Jul 1. PMID 25827285
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 175

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014017.2 → NP_001014039.1  zinc finger protein 175

    See identical proteins and their annotated locations for NP_001014039.1

    Status: PROVISIONAL

    Source sequence(s)
    BC087070
    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1
    Related
    ENSRNOP00000024662.6, ENSRNOT00000024662.8
    Conserved Domains (5) summary
    smart00349
    Location:27 → 81
    KRAB; krueppel associated box
    COG5048
    Location:346 → 538
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:499 → 582
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:449 → 469
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    103163570..103222203
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006229046.5 → XP_006229108.1  zinc finger protein 175 isoform X1

    See identical proteins and their annotated locations for XP_006229108.1

    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1
    Conserved Domains (5) summary
    smart00349
    Location:27 → 81
    KRAB; krueppel associated box
    COG5048
    Location:346 → 538
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:499 → 582
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:449 → 469
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

  2. XM_039111789.2 → XP_038967717.1  zinc finger protein 175 isoform X1

    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1
    Conserved Domains (5) summary
    smart00349
    Location:27 → 81
    KRAB; krueppel associated box
    COG5048
    Location:346 → 538
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:499 → 582
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:449 → 469
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

  3. XM_063261749.1 → XP_063117819.1  zinc finger protein 175 isoform X2

  4. XM_017589129.3 → XP_017444618.1  zinc finger protein 175 isoform X1

    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1
    Conserved Domains (5) summary
    smart00349
    Location:27 → 81
    KRAB; krueppel associated box
    COG5048
    Location:346 → 538
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:499 → 582
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:449 → 469
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

  5. XM_063261741.1 → XP_063117811.1  zinc finger protein 175 isoform X1

    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1

  6. XM_063261747.1 → XP_063117817.1  zinc finger protein 175 isoform X1

    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1

  7. XM_063261731.1 → XP_063117801.1  zinc finger protein 175 isoform X1

    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1

  8. XM_006229047.5 → XP_006229109.1  zinc finger protein 175 isoform X1

    See identical proteins and their annotated locations for XP_006229109.1

    UniProtKB/TrEMBL
    A0A9K3Y6N2, F7EPA9, Q5PQR1
    Conserved Domains (5) summary
    smart00349
    Location:27 → 81
    KRAB; krueppel associated box
    COG5048
    Location:346 → 538
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:499 → 582
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:449 → 469
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:573 → 598
    zf-H2C2_2; Zinc-finger double domain

  9. XM_063261753.1 → XP_063117823.1  zinc finger protein 175 isoform X3

    UniProtKB/TrEMBL
    D3ZXU3
    Related
    ENSRNOP00000103128.1, ENSRNOT00000157655.1

RNA

  1. XR_010052073.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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