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Zfp579 zinc finger protein 579 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308339, updated on 4-Jan-2025

Summary

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Official Symbol
Zfp579provided by RGD
Official Full Name
zinc finger protein 579provided by RGD
Primary source
RGD:1308475
See related
EnsemblRapid:ENSRNOG00000016608 AllianceGenome:RGD:1308475
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf579
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF579 (zinc finger protein 579). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Lung (RPKM 22.1), Heart (RPKM 16.3) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp579 in Genome Data Viewer
Location:
1q12
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (77876367..77879591)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (68847547..68850751)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72397887..72402329)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 524 Neighboring gene FLT3-interacting zinc finger 1 Neighboring gene SH3 domain binding kinase family, member 3 Neighboring gene SH3 domain binding kinase family, member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 579

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126276.1 → NP_001119748.1  zinc finger protein 579

    See identical proteins and their annotated locations for NP_001119748.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161912
    UniProtKB/TrEMBL
    B1WBW3
    Conserved Domains (3) summary
    COG5048
    Location:45 → 107
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:74 → 96
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    77876367..77879591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228256.5 → XP_006228318.1  zinc finger protein 579 isoform X1

    See identical proteins and their annotated locations for XP_006228318.1

    UniProtKB/TrEMBL
    B1WBW3
    Related
    ENSRNOP00000022349.4, ENSRNOT00000022349.6
    Conserved Domains (3) summary
    COG5048
    Location:45 → 107
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:74 → 96
    zf-C2H2; Zinc finger, C2H2 type
Nucleotide Protein Strain
Heading Accession and Version

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