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Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307897, updated on 27-Nov-2024

Summary

Official Symbol
Sdr42e1provided by RGD
Official Full Name
short chain dehydrogenase/reductase family 42E, member 1provided by RGD
Primary source
RGD:1308481
See related
EnsemblRapid:ENSRNOG00000051819 AllianceGenome:RGD:1308481
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hspc105; RGD1308481
Summary
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in steroid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SDR42E1 (short chain dehydrogenase/reductase family 42E, member 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 127.9), Kidney (RPKM 18.5) and 6 other tissues See more
Orthologs
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Genomic context

See Sdr42e1 in Genome Data Viewer
Location:
19q12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (62624130..62636652, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (45715366..45727901, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (50207960..50220455, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene c-Maf-inducing protein Neighboring gene uncharacterized LOC102548350 Neighboring gene uncharacterized LOC120098622 Neighboring gene phospholipase C, gamma 2 Neighboring gene uncharacterized LOC120098492 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 2 Neighboring gene M phase phosphoprotein 6

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
short-chain dehydrogenase/reductase family 42E member 1
NP_001258198.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271269.1NP_001258198.1  short-chain dehydrogenase/reductase family 42E member 1

    See identical proteins and their annotated locations for NP_001258198.1

    Status: VALIDATED

    Source sequence(s)
    BI295943, BQ196592, FN798906, FQ103187, JAXUCZ010000019
    UniProtKB/TrEMBL
    A0A0G2JT58, A0A8I6GEP8, A6IZH6
    Related
    ENSRNOP00000068579.2, ENSRNOT00000079760.3
    Conserved Domains (1) summary
    cl21454
    Location:10350
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    62624130..62636652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)