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Mon1b MON1 homolog B, secretory trafficking associated [ Rattus norvegicus (Norway rat) ]

Gene ID: 307868, updated on 27-Nov-2024

Summary

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Official Symbol
Mon1bprovided by RGD
Official Full Name
MON1 homolog B, secretory trafficking associatedprovided by RGD
Primary source
RGD:1309977
See related
EnsemblRapid:ENSRNOG00000084202 AllianceGenome:RGD:1309977
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309977
Summary
Predicted to be involved in early viral transcription and late viral transcription. Predicted to be located in cytoplasm. Predicted to be part of Mon1-Ccz1 complex. Orthologous to human MON1B (MON1 homolog B, secretory trafficking associated). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 181.0), Thymus (RPKM 103.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mon1b in Genome Data Viewer
Location:
19q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (58526503..58534478)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (41617372..41625347)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (45938433..45946647)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483647 Neighboring gene cell division cycle 34, ubiqiutin conjugating enzyme, pseudogene 1 Neighboring gene synaptonemal complex central element protein 1-like Neighboring gene small nucleolar RNA SNORA40 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 18 Neighboring gene S-phase kinase-associated protein 1, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. HSV-1 stimulation-related protein HSRG1 inhibits viral gene transcriptional elongation by interacting with Cyclin T2. Wu W, et al. Sci China Life Sci, 2011 Apr. PMID 21509660
  2. Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux. Vaites LP, et al. Mol Cell Biol, 2018 Jan 1. PMID 29038162, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in early viral transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in late viral transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in protein targeting to vacuole IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Mon1-Ccz1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mon1-Ccz1 complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
vacuolar fusion protein MON1 homolog B
Names
MON1 secretory trafficking family member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399113.1 → NP_001386042.1  vacuolar fusion protein MON1 homolog B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/TrEMBL
    A0A8I6G3S1, A6IZD1
    Conserved Domains (2) summary
    PHA03169
    Location:26 → 140
    PHA03169; hypothetical protein; Provisional
    pfam03164
    Location:144 → 561
    Mon1; Trafficking protein Mon1

  2. NM_001399114.1 → NP_001386043.1  vacuolar fusion protein MON1 homolog B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/TrEMBL
    A0A8I6G3S1, A6IZD1
    Related
    ENSRNOP00000079817.1, ENSRNOT00000098873.2
    Conserved Domains (2) summary
    PHA03169
    Location:26 → 140
    PHA03169; hypothetical protein; Provisional
    pfam03164
    Location:144 → 561
    Mon1; Trafficking protein Mon1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    58526503..58534478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001107433.1: Suppressed sequence

    Description
    NM_001107433.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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