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Tango6 transport and golgi organization 6 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 307816, updated on 4-Jan-2025

Summary

Official Symbol
Tango6provided by RGD
Official Full Name
transport and golgi organization 6 homologprovided by RGD
Primary source
RGD:1559841
See related
EnsemblRapid:ENSRNOG00000022524 AllianceGenome:RGD:1559841
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1559841
Summary
Predicted to be involved in protein secretion. Orthologous to human TANGO6 (transport and golgi organization 6 homolog). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 55.7), Adrenal (RPKM 44.5) and 9 other tissues See more
Orthologs
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Genomic context

See Tango6 in Genome Data Viewer
Location:
19q12
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (51479384..51667142)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (34569588..34757362)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (38846204..39052940)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene cadherin 3 Neighboring gene cadherin 1 Neighboring gene hyaluronan synthase 3 Neighboring gene chromosome transmission fidelity factor 8 Neighboring gene DERPC proline and glycine rich nuclear protein Neighboring gene UTP4 small subunit processome component

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
transport and Golgi organization protein 6 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427103.1NP_001414032.1  transport and Golgi organization protein 6 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/TrEMBL
    A6IYX6, D4AAU1
    Related
    ENSRNOP00000099556.1, ENSRNOT00000138119.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    51479384..51667142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063278042.1XP_063134112.1  transport and Golgi organization protein 6 homolog isoform X1

    UniProtKB/TrEMBL
    A6IYX6
    Related
    ENSRNOP00000103388.1, ENSRNOT00000156495.1
  2. XM_006255568.5XP_006255630.1  transport and Golgi organization protein 6 homolog isoform X2

    UniProtKB/TrEMBL
    A6IYX6, D4A9F1
    Related
    ENSRNOP00000111688.1, ENSRNOT00000170748.1
    Conserved Domains (3) summary
    pfam10304
    Location:9731005
    RTP1_C2; Required for nuclear transport of RNA pol II C-terminus 2
    pfam10363
    Location:772875
    RTP1_C1; Required for nuclear transport of RNA pol II C-terminus 1
    sd00044
    Location:810838
    HEAT; HEAT repeat [structural motif]
  3. XM_039098139.2XP_038954067.1  transport and Golgi organization protein 6 homolog isoform X3