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Adgrg5 adhesion G protein-coupled receptor G5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307645, updated on 4-Jan-2025

Summary

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Official Symbol
Adgrg5provided by RGD
Official Full Name
adhesion G protein-coupled receptor G5provided by RGD
Primary source
RGD:1305559
See related
EnsemblRapid:ENSRNOG00000039891 AllianceGenome:RGD:1305559
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gpr114
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human ADGRG5 (adhesion G protein-coupled receptor G5). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 32.4), Thymus (RPKM 16.7) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Adgrg5 in Genome Data Viewer
Location:
19p13
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (10080800..10104659, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (10074787..10098640, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10495517..10514701, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor G3 Neighboring gene adhesion G protein-coupled receptor G1 Neighboring gene coiled-coil domain containing 102A Neighboring gene docking protein 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
adhesion G-protein coupled receptor G5
Names
G protein-coupled receptor 114
G protein-coupled receptor 114-like
probable G-protein coupled receptor 114

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107410.1 → NP_001100880.1  adhesion G-protein coupled receptor G5 precursor

    See identical proteins and their annotated locations for NP_001100880.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474006
    UniProtKB/TrEMBL
    A6JY35
    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:242 → 267
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:242 → 513
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    10080800..10104659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039097707.2 → XP_038953635.1  adhesion G-protein coupled receptor G5 isoform X10

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 349
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_039097706.2 → XP_038953634.1  adhesion G-protein coupled receptor G5 isoform X10

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 349
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_063277985.1 → XP_063134055.1  adhesion G-protein coupled receptor G5 isoform X3

  4. XM_008772297.2 → XP_008770519.2  adhesion G-protein coupled receptor G5 isoform X1

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:242 → 267
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:242 → 348
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  5. XM_063277986.1 → XP_063134056.1  adhesion G-protein coupled receptor G5 isoform X8

  6. XM_008772299.3 → XP_008770521.2  adhesion G-protein coupled receptor G5 isoform X4

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 322
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  7. XM_008772307.4 → XP_008770529.2  adhesion G-protein coupled receptor G5 isoform X6

    UniProtKB/TrEMBL
    A6JY35
    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:242 → 267
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:242 → 513
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  8. XM_008772298.3 → XP_008770520.2  adhesion G-protein coupled receptor G5 isoform X2

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 272
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  9. XM_017601274.3 → XP_017456763.2  adhesion G-protein coupled receptor G5 isoform X7

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 315
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  10. XM_008772306.4 → XP_008770528.2  adhesion G-protein coupled receptor G5 isoform X5

    UniProtKB/TrEMBL
    F1M644
    Related
    ENSRNOP00000057982.4, ENSRNOT00000061270.6
    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 514
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  11. XM_063277987.1 → XP_063134057.1  adhesion G-protein coupled receptor G5 isoform X9

  12. XM_008772301.4 → XP_008770523.1  adhesion G-protein coupled receptor G5 isoform X10

    See identical proteins and their annotated locations for XP_008770523.1

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 349
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  13. XM_063277989.1 → XP_063134059.1  adhesion G-protein coupled receptor G5 isoform X13

  14. XM_063277988.1 → XP_063134058.1  adhesion G-protein coupled receptor G5 isoform X12

  15. XM_039097708.2 → XP_038953636.1  adhesion G-protein coupled receptor G5 isoform X11

    Conserved Domains (3) summary
    pfam01825
    Location:184 → 228
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:243 → 268
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243 → 269
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RNA

  1. XR_005496649.2 RNA Sequence

  2. XR_005496648.2 RNA Sequence

  3. XR_005496650.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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