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vegfaa - vascular endothelial growth factor Aa

Enables growth factor activity. Involved in phosphorylation. Acts upstream of or within several processes, including circulatory system development; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of vasculature development. Located in extracellular region. Is expressed in several structures, including cardiovascular system; mesoderm; nervous system; pleuroperitoneal region; and podocyte. Used to study proteinuria. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human VEGFA (vascular endothelial growth factor A). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa