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Arl10 ARF like GTPase 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306767, updated on 27-Nov-2024

Summary

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Official Symbol
Arl10provided by RGD
Official Full Name
ARF like GTPase 10provided by RGD
Primary source
RGD:1303298
See related
EnsemblRapid:ENSRNOG00000045948 AllianceGenome:RGD:1303298
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be located in mitochondrion. Orthologous to human ARL10 (ADP ribosylation factor like GTPase 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 52.7), Lung (RPKM 45.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Arl10 in Genome Data Viewer
Location:
17p14
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (10035320..10043732, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (10030213..10038625, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (10567064..10575518, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene HIG1 hypoxia inducible domain family, member 2A Neighboring gene NOP16 nucleolar protein Neighboring gene KIAA1191 homolog Neighboring gene SUMO-interacting motifs containing 1 Neighboring gene uncharacterized LOC134482678 Neighboring gene uncharacterized LOC134482679

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors. Louro R, et al. Biochem Biophys Res Commun, 2004 Apr 9. PMID 15033445
  2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
ADP-ribosylation factor-like protein 10
Names
ADP-ribosylation factor like GTPase 10
ADP-ribosylation factor-like 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399321.1 → NP_001386250.1  ADP-ribosylation factor-like protein 10 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A6KAY8
    Related
    ENSRNOP00000095832.1, ENSRNOT00000108677.2
    Conserved Domains (1) summary
    cl38936
    Location:78 → 236
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. NM_207165.2 → NP_997048.1  ADP-ribosylation factor-like protein 10 isoform 2

    See identical proteins and their annotated locations for NP_997048.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A6KAY9, M0RBH4, Q6IMA8
    Related
    ENSRNOP00000066910.1, ENSRNOT00000073186.4
    Conserved Domains (1) summary
    cl21455
    Location:28 → 186
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    10035320..10043732 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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