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Nxnl1 nucleoredoxin-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306342, updated on 4-Jan-2025

Summary

Symbol
Nxnl1provided by RGD
Full Name
nucleoredoxin-like 1provided by RGD
Primary source
RGD:1308296
See related
AllianceGenome:RGD:1308296
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Txnl6
Summary
Predicted to enable receptor ligand activity. Predicted to be involved in photoreceptor cell maintenance. Orthologous to human NXNL1 (nucleoredoxin like 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Testes (RPKM 13.2), Adrenal (RPKM 10.4) and 7 other tissues See more
Orthologs
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Genomic context

See Nxnl1 in Genome Data Viewer
Location:
16p14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (18303454..18311510, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (18270604..18279797, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (19992211..19996815, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase like 1 Neighboring gene multivesicular body subunit 12A Neighboring gene transmembrane protein 221 Neighboring gene solute carrier family 27 member 1 Neighboring gene 6-phosphogluconolactonase Neighboring gene niban apoptosis regulator 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
nucleoredoxin-like protein 1
Names
thioredoxin-like 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271341.2NP_001258270.1  nucleoredoxin-like protein 1

    See identical proteins and their annotated locations for NP_001258270.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A0A0G2K4X6
    Conserved Domains (1) summary
    cd03008
    Location:8153
    TryX_like_RdCVF; Tryparedoxin (TryX)-like family, Rod-derived cone viability factor (RdCVF) subfamily; RdCVF is a thioredoxin (TRX)-like protein specifically expressed in photoreceptors. RdCVF was isolated and identified as a factor that supports cone survival in retinal ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    18303454..18311510 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039094485.2XP_038950413.1  nucleoredoxin-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K4X6
    Conserved Domains (1) summary
    cd03008
    Location:8153
    TryX_like_RdCVF; Tryparedoxin (TryX)-like family, Rod-derived cone viability factor (RdCVF) subfamily; RdCVF is a thioredoxin (TRX)-like protein specifically expressed in photoreceptors. RdCVF was isolated and identified as a factor that supports cone survival in retinal ...

RNA

  1. XR_001841535.3 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001107302.2: Suppressed sequence

    Description
    NM_001107302.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.