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Eaf1 ELL associated factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306261, updated on 27-Nov-2024

Summary

Official Symbol
Eaf1provided by RGD
Official Full Name
ELL associated factor 1provided by RGD
Primary source
RGD:1310057
See related
EnsemblRapid:ENSRNOG00000019559 AllianceGenome:RGD:1310057
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable transcription elongation factor activity. Predicted to be involved in regulation of transcription elongation by RNA polymerase II and transcription elongation by RNA polymerase II. Predicted to be located in intercellular bridge and nuclear body. Predicted to be part of transcription elongation factor complex. Orthologous to human EAF1 (ELL associated factor 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 77.1), Thymus (RPKM 62.9) and 9 other tissues See more
Orthologs
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Genomic context

See Eaf1 in Genome Data Viewer
Location:
16p16
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (6704727..6719476)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (6698322..6713071)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (7588217..7602966)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482448 Neighboring gene SH3-domain binding protein 5 Neighboring gene uncharacterized LOC134482449 Neighboring gene methyltransferase 6, tRNA N3-cytidine Neighboring gene collagen like tail subunit of asymmetric acetylcholinesterase Neighboring gene uncharacterized LOC134482450 Neighboring gene 2-hydroxyacyl-CoA lyase 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transcription elongation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transcription elongation factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in regulation of transcription elongation by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in intercellular bridge IEA
Inferred from Electronic Annotation
more info
 
located_in intercellular bridge ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of super elongation complex IEA
Inferred from Electronic Annotation
more info
 
part_of transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transcription elongation factor complex ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107293.1NP_001100763.1  ELL-associated factor 1

    See identical proteins and their annotated locations for NP_001100763.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474046
    UniProtKB/TrEMBL
    A6KFY7, D4A2G7
    Related
    ENSRNOP00000026525.5, ENSRNOT00000026525.7
    Conserved Domains (1) summary
    pfam09816
    Location:102200
    EAF; RNA polymerase II transcription elongation factor

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    6704727..6719476
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)