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Fmo6 flavin containing monooxygenase 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304922, updated on 2-Nov-2024

Summary

Official Symbol
Fmo6provided by RGD
Official Full Name
flavin containing monooxygenase 6provided by RGD
Primary source
RGD:1559491
See related
EnsemblRapid:ENSRNOG00000049851 AllianceGenome:RGD:1559491
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1559491
Summary
Predicted to enable N,N-dimethylaniline monooxygenase activity. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human FMO6P (flavin containing dimethylaniline monoxygenase 6, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 28.6), Liver (RPKM 25.0) and 4 other tissues See more
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Genomic context

See Fmo6 in Genome Data Viewer
Location:
13q22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (77793600..77821958, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (75256617..75288167, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (80791355..80819915, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene heat shock protein 90 alpha family class A member 1, pseudogene 13 Neighboring gene uncharacterized LOC134481523 Neighboring gene flavin containing dimethylaniline monoxygenase 3 Neighboring gene maestro heat-like repeat family member 9 Neighboring gene small nucleolar RNA SNORA17

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N,N-dimethylaniline monooxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables hypotaurine monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative dimethylaniline monooxygenase [N-oxide-forming] 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    77793600..77821958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006250206.5XP_006250268.1  putative dimethylaniline monooxygenase [N-oxide-forming] 6

    See identical proteins and their annotated locations for XP_006250268.1

    UniProtKB/TrEMBL
    M0R553
    Related
    ENSRNOP00000064509.1, ENSRNOT00000072922.3
    Conserved Domains (2) summary
    pfam00743
    Location:2532
    FMO-like; Flavin-binding monooxygenase-like
    cl21454
    Location:6220
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins