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gata2a - GATA binding protein 2a

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within circulatory system development; hemopoiesis; and ventral spinal cord interneuron differentiation. Predicted to be active in nucleus. Is expressed in several structures, including hematopoietic system; mesoderm; nervous system; presumptive structure; and trunk vasculature. Human ortholog(s) of this gene implicated in acute myeloid leukemia; depressive disorder; immunodeficiency 21; myelodysplastic syndrome; and myeloid leukemia. Orthologous to human GATA2 (GATA binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa