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Acad10 acyl-CoA dehydrogenase family, member 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304500, updated on 27-Nov-2024

Summary

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Official Symbol
Acad10provided by RGD
Official Full Name
acyl-CoA dehydrogenase family, member 10provided by RGD
Primary source
RGD:1310159
See related
EnsemblRapid:ENSRNOG00000037815 AllianceGenome:RGD:1310159
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310159
Summary
Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Orthologous to human ACAD10 (acyl-CoA dehydrogenase family member 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 319.9), Adrenal (RPKM 247.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Acad10 in Genome Data Viewer
Location:
12q16
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (40561900..40604378)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (34901211..34943973)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (40417918..40460562)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene ataxin 2 Neighboring gene F-box protein 22, pseudogene 1 Neighboring gene BRCA1 associated protein Neighboring gene aldehyde dehydrogenase 2 family member Neighboring gene MAPK activated protein kinase 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. Bhatnagar S, et al. J Biol Chem, 2014 Sep 5. PMID 25002582, Free PMC Article
  2. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
  3. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
  4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC187436

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
acyl-CoA dehydrogenase family member 10
Names
acyl-Coenzyme A dehydrogenase family, member 10
NP_001385719.1
XP_038946092.1
XP_038946093.1
XP_063127408.1
XP_063127409.1
XP_063127410.1
XP_063127411.1
XP_063127412.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398790.1 → NP_001385719.1  acyl-CoA dehydrogenase family member 10

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    B5DEF6, F1LSP2
    Related
    ENSRNOP00000092331.2, ENSRNOT00000104824.2
    Conserved Domains (2) summary
    PLN02876
    Location:257 → 1061
    PLN02876; acyl-CoA dehydrogenase
    TIGR02247
    Location:41 → 247
    HAD-1A3-hyp; epoxide hydrolase N-terminal domain-like phosphatase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    40561900..40604378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063271338.1 → XP_063127408.1  acyl-CoA dehydrogenase family member 10 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AV92

  2. XM_039090164.2 → XP_038946092.1  acyl-CoA dehydrogenase family member 10 isoform X2

    UniProtKB/TrEMBL
    A0A8I6AGW1
    Related
    ENSRNOP00000097994.2, ENSRNOT00000096999.2
    Conserved Domains (2) summary
    PLN02876
    Location:257 → 1013
    PLN02876; acyl-CoA dehydrogenase
    TIGR02247
    Location:41 → 247
    HAD-1A3-hyp; epoxide hydrolase N-terminal domain-like phosphatase

  3. XM_039090165.2 → XP_038946093.1  acyl-CoA dehydrogenase family member 10 isoform X4

    UniProtKB/TrEMBL
    A0A8I6AGW1
    Conserved Domains (2) summary
    PLN02876
    Location:257 → 939
    PLN02876; acyl-CoA dehydrogenase
    TIGR02247
    Location:41 → 247
    HAD-1A3-hyp; epoxide hydrolase N-terminal domain-like phosphatase

  4. XM_063271339.1 → XP_063127409.1  acyl-CoA dehydrogenase family member 10 isoform X3

  5. XM_063271340.1 → XP_063127410.1  acyl-CoA dehydrogenase family member 10 isoform X5

  6. XM_063271341.1 → XP_063127411.1  acyl-CoA dehydrogenase family member 10 isoform X6

  7. XM_063271342.1 → XP_063127412.1  acyl-CoA dehydrogenase family member 10 isoform X6

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001134537.1: Suppressed sequence

    Description
    NM_001134537.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: ACAD10 (GeneID:80724).
Nucleotide Protein Strain
Heading Accession and Version

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