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Cldn17 claudin 17 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304125, updated on 9-Dec-2024

Summary

Official Symbol
Cldn17provided by RGD
Official Full Name
claudin 17provided by RGD
Primary source
RGD:1307462
See related
AllianceGenome:RGD:1307462
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable channel activity and paracellular tight junction channel activity. Predicted to be involved in bicellular tight junction assembly; cell adhesion; and paracellular transport. Predicted to be located in tight junction. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN17 (claudin 17). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Cldn17 in Genome Data Viewer
Location:
11q11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (41313675..41314851, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (27827454..27828630, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (28477184..28478360, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene glutamate ionotropic receptor kainate type subunit 1 Neighboring gene sorting nexin-1-like Neighboring gene uncharacterized LOC108352301 Neighboring gene KAT8 regulatory NSL complex subunit 2, pseudogene 1 Neighboring gene claudin 8

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables channel activity ISO
Inferred from Sequence Orthology
more info
 
enables paracellular tight junction channel activity ISO
Inferred from Sequence Orthology
more info
 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in paracellular transport ISO
Inferred from Sequence Orthology
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in tight junction ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107112.1NP_001100582.1  claudin-17

    See identical proteins and their annotated locations for NP_001100582.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473989
    UniProtKB/TrEMBL
    A6JL93, D4A6L7
    Conserved Domains (1) summary
    cl21598
    Location:6182
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    41313675..41314851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)