Wnt9b Wnt family member 9B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Wnt9bprovided by RGD
Official Full Name: Wnt family member 9Bprovided by RGD
Primary source: RGD:1309574
See related: EnsemblRapid:ENSRNOG00000003807 AllianceGenome:RGD:1309574
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable co-receptor binding activity; cytokine activity; and frizzled binding activity. Predicted to be involved in several processes, including Wnt signaling pathway; midbrain dopaminergic neuron differentiation; and negative regulation of stem cell population maintenance. Predicted to act upstream of or within several processes, including chordate embryonic development; kidney development; and reproductive structure development. Predicted to be active in extracellular space. Orthologous to human WNT9B (Wnt family member 9B). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 14.4), Testes (RPKM 12.7) and 4 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.1

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (89135362..89157065, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (88635330..88657035, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (91785892..91808061, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:471334 (e-PCR)
- UniSTS:471334

Wnt9b (e-PCR), detects polymorphism
- UniSTS:471334

RH127598 (e-PCR)
- UniSTS:210908

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables co-receptor binding	ISO Inferred from Sequence Orthology more info
enables cytokine activity	IBA Inferred from Biological aspect of Ancestor more info
enables frizzled binding	IBA Inferred from Biological aspect of Ancestor more info
enables receptor ligand activity	ISO Inferred from Sequence Orthology more info
enables signaling receptor binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within Wnt signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within Wnt signaling pathway, planar cell polarity pathway	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within branching involved in ureteric bud morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within branching morphogenesis of an epithelial tube	ISO Inferred from Sequence Orthology more info
involved_in canonical Wnt signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within canonical Wnt signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in canonical Wnt signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in cell fate commitment	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cellular response to starvation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within collecting duct development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within embryonic cranial skeleton morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within establishment of planar polarity involved in nephron morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within in utero embryonic development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within kidney development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within kidney morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within kidney rudiment formation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within male genitalia development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within mesenchymal stem cell maintenance involved in nephron morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within mesonephric duct formation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within mesonephric tubule development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within metanephric tubule development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within metanephric tubule formation	ISO Inferred from Sequence Orthology more info
involved_in midbrain dopaminergic neuron differentiation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of stem cell population maintenance	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within nephron tubule morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in neuron differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in non-canonical Wnt signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of catalytic activity	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of asymmetric cell division	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of protein phosphorylation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of tube size	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within roof of mouth development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within uterus morphogenesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein Wnt-9b

Names: wingless related MMTV integration site 9B; wingless-type MMTV integration site 9B; wingless-type MMTV integration site family, member 9B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.