U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Msl1 MSL complex subunit 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303514, updated on 2-Nov-2024

Summary

Official Symbol
Msl1provided by RGD
Official Full Name
MSL complex subunit 1provided by RGD
Primary source
RGD:1564778
See related
EnsemblRapid:ENSRNOG00000009643 AllianceGenome:RGD:1564778
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564778
Summary
Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in chromatin remodeling and positive regulation of DNA-templated transcription. Predicted to be located in nuclear speck. Predicted to be part of MSL complex. Orthologous to human MSL1 (MSL complex subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 247.2), Brain (RPKM 214.2) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Msl1 in Genome Data Viewer
Location:
10q31
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (84251362..84263384)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (83755380..83767147)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (86710925..86722659)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene thyroid hormone receptor alpha Neighboring gene uncharacterized LOC108352130 Neighboring gene nuclear receptor subfamily 1, group D, member 1 Neighboring gene CASC3 exon junction complex subunit Neighboring gene Rap guanine nucleotide exchange factor like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in chromatin remodeling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of MSL complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of MSL complex ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
male-specific lethal 1 homolog
Names
male specific lethal 1 homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107048.1NP_001100518.1  male-specific lethal 1 homolog

    See identical proteins and their annotated locations for NP_001100518.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A6HIV1, D3ZBD0
    Related
    ENSRNOP00000012812.5, ENSRNOT00000012812.9
    Conserved Domains (1) summary
    pfam15275
    Location:460576
    PEHE; PEHE domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    84251362..84263384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006247304.5XP_006247366.1  male-specific lethal 1 homolog isoform X1

    See identical proteins and their annotated locations for XP_006247366.1

    UniProtKB/TrEMBL
    A0A8I5ZM69, A6HIV0
    Related
    ENSRNOP00000079028.1, ENSRNOT00000107825.2
    Conserved Domains (1) summary
    pfam15275
    Location:476592
    PEHE; PEHE domain