Surf6 surfeit 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Surf6provided by RGD
Full Name: surfeit 6provided by RGD
Primary source: RGD:1307382
See related: EnsemblRapid:ENSRNOG00000005031 AllianceGenome:RGD:1307382
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA binding activity; RNA binding activity; and molecular condensate scaffold activity. Predicted to be involved in ribosomal large subunit biogenesis and ribosomal small subunit biogenesis. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in chromosome; granular component; and nucleoplasm. Predicted to be active in nucleolus. Orthologous to human SURF6 (surfeit 6). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Thymus (RPKM 126.6), Spleen (RPKM 91.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3p13

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (30619525..30630388, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (10221450..10232306, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (5441404..5452156, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

BF396659 (e-PCR)
- UniSTS:245832

AW212655 (e-PCR)
- UniSTS:178591

RH133460 (e-PCR)
- UniSTS:216743

RH141946 (e-PCR)
- UniSTS:223937

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables DNA binding	ISO Inferred from Sequence Orthology more info
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables molecular condensate scaffold activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in ribosomal large subunit biogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal small subunit biogenesis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ribosome biogenesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in chromosome	ISO Inferred from Sequence Orthology more info
located_in granular component	ISO Inferred from Sequence Orthology more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: surfeit locus protein 6

Names: surfeit gene 6; surfeit locus protein 6-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001015014.1 → NP_001015014.1 surfeit locus protein 6

See identical proteins and their annotated locations for NP_001015014.1

Status: PROVISIONAL

Source sequence(s)

BC091270

UniProtKB/TrEMBL

Q5BJZ4

Conserved Domains (1) summary

pfam04935
Location:161 → 335

SURF6; Surfeit locus protein 6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

30619525..30630388 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006233784.3 → XP_006233846.1 surfeit locus protein 6 isoform X1

UniProtKB/TrEMBL

F7F149

Related

ENSRNOP00000006699.4, ENSRNOT00000006699.6

Conserved Domains (1) summary

pfam04935
Location:156 → 313

SURF6; Surfeit locus protein 6