tdgf1 - teratocarcinoma-derived growth factor 1
Predicted to enable activin receptor binding activity and nodal binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and regionalization. Located in external side of plasma membrane. Is expressed in several structures, including EVL; cardiovascular system; diencephalon; ectoderm; and mesoderm. Used to study neural tube defect. Human ortholog(s) of this gene implicated in colon cancer and congenital heart disease. Orthologous to several human genes including CRIPTO (cripto, EGF-CFC family member). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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