U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Paqr4 progestin and adipoQ receptor family member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 302967, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Paqr4provided by RGD
Official Full Name
progestin and adipoQ receptor family member 4provided by RGD
Primary source
RGD:1309533
See related
EnsemblRapid:ENSRNOG00000069091 AllianceGenome:RGD:1309533
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable molecular adaptor activity. Predicted to be involved in protein stabilization and regulation of ceramide biosynthetic process. Predicted to be located in Golgi membrane. Orthologous to human PAQR4 (progestin and adipoQ receptor family member 4). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 95.5), Lung (RPKM 60.7) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Paqr4 in Genome Data Viewer
Location:
10q12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (13263559..13267237, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (12758970..12762649, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (13072252..13075866, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene vegetative cell wall protein gp1-like Neighboring gene glycine rich extracellular protein 1 Neighboring gene protein kinase, membrane associated tyrosine/threonine 1 Neighboring gene kringle containing transmembrane protein 2 Neighboring gene RIKEN cDNA 9530082P21 gene like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. Tang YT, et al. J Mol Evol, 2005 Sep. PMID 16044242
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC109357

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular adaptor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of ceramide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
progestin and adipoQ receptor family member 4
Names
progestin and adipoQ receptor family member IV

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017377.2 → NP_001017377.1  progestin and adipoQ receptor family member 4

    See identical proteins and their annotated locations for NP_001017377.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I6A5M9, Q568Z3
    Related
    ENSRNOP00000087345.1, ENSRNOT00000116169.2
    Conserved Domains (1) summary
    cl03831
    Location:43 → 254
    HlyIII; Haemolysin-III related

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    13263559..13267237 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085852.2 → XP_038941780.1  progestin and adipoQ receptor family member 4 isoform X2

    Conserved Domains (1) summary
    cl03831
    Location:43 → 125
    HlyIII; Haemolysin-III related

  2. XM_006245871.5 → XP_006245933.1  progestin and adipoQ receptor family member 4 isoform X1

    Conserved Domains (1) summary
    cl03831
    Location:49 → 210
    HlyIII; Haemolysin-III related
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools