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tfa - transferrin-a

Predicted to enable metal ion binding activity. Acts upstream of or within hemoglobin biosynthetic process; iron ion transport; and response to bacterium. Predicted to be located in extracellular region. Predicted to be active in endosome; extracellular space; and plasma membrane. Is expressed in several structures, including ball; liver; ovary; renal system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); atransferrinemia; carcinoma (multiple); glucose metabolism disease (multiple); and restless legs syndrome. Orthologous to human LTF (lactotransferrin) and TF (transferrin). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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Species Gene Architecture aa